Accurate medical access to those pits on the road

Precision medicine, also known as personalized medicine, refers to the combination of proteome, metabolome and other related environmental information based on personal genomic information, to design the best treatment plan for patients, in order to maximize the treatment effect and minimize side effects. A customized medical model. In recent years, "precise medical care" has become a hot spot in the medical industry at home and abroad. Below, Xiaobian will take stock of what happened in 2016 about precision medicine.

In February 2016, researchers at the University of Iowa in the United States applied individualized proteomics to develop a precise treatment strategy for a patient with ocular diseases, and published the results in the international academic journal JAMA Ophthalmology. An important step in the accurate diagnosis and treatment of diseases.

On March 5th, Precision Medicine (genomics) was selected into 100 major projects in the “13th Five-Year Plan”. On March 8th, the “Notice of the Ministry of Science and Technology on Issuing the 2016 Key Project Declaration Guide for Key Specialized Research and Development Programs for Accurate Medical Research” (referred to as the “National Guide”) was announced on March 8th, which opened a major special scientific research action for precision medicine. The prelude. The national guidelines are clear, and precision medicine will be one of the key priorities for this year's priority, and will officially enter the implementation phase.

On April 15, the National Health and Family Planning Commission and the Ministry of Science and Technology organized more than 30 experts in the fields of biomedicine, bioinformatics big data and clinical medicine, as well as the Chinese Academy of Sciences, the Ministry of Health and the National Natural Science Foundation. Leaders will jointly discuss the implementation principles, objectives and key contents of the precision medical research plan, and plan our medical development strategy.

In May, Australian Prime Minister Malcolm Turnbull announced the Zero Childhood Cancer Program. The program aims to use genomic technology to provide individualized treatment strategies for childhood cancers that are currently incurable.

In June, the White House issued a draft data security framework related to precision medical plans. The draft recommended that participants in precision medicine should establish a safety plan based on overall risk and establish a corresponding management system to ensure data security. At the same time, the White House also requires participating agencies to find third-party agencies to help them test and confirm the security of existing data.

On June 25th, the National Science and Technology Management Information System Public Service Platform issued the “Notice on Publicizing the 2016 Project Arrangement for the National Key R&D Program “Precision Medical Research”, and the “Special Medical Research” key special project is expected to enter the review session 2016. The annual project information is publicized. 61 projects entered the public notice list, and the central government's financial support totaled 640 million yuan.

At the end of June, the French government announced an investment of 670 million euros to launch a genomic and individualized medical project, and named it: France Genomic Medicine 2025. The project aims to improve national medical diagnosis and disease prevention capabilities. It is expected to establish 12 gene sequencing platforms and 2 national data centers nationwide.

On July 7, the FDA issued two draft guidelines, “FDA-Based Oversight Standards for In Vitro Diagnosis of Genital Diseases Based on NGS Technology.” “Using the Public Human Genetic Difference Database to Support the Clinical Effectiveness of NGS-Based In Vitro Diagnostics ", aimed at further accelerating the promotion of precision medical plans.

In early July, Obama announced that he would invest $55 million in the fiscal year to establish a precision medical public database that would cover the detailed health information of more than 1 million volunteers for disease research and the beginning of personalized medicines and therapies.

In July, led by the National Development and Reform Commission, the Zhejiang Provincial Development and Reform Commission issued the “Zhejiang Genetic Testing Technology Application and Demonstration Center Construction Plan” (Zhefa Development High Technology [2016] No. 65, hereinafter referred to as “Demonstration Center Construction Plan”), officially approved The construction of a demonstration center such as the “Application of Gene Detection Technology for Genes” is planned to be completed in 2017.

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